Rahul Sharma (Editor)


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Species  Human
Entrez  129685
Human  Mouse
Ensembl  ENSG00000137413
Aliases  TAF8, 43, II, TAF, TAFII-43, TAFII43, TBN, TATA-box binding protein associated factor 8
External IDs  MGI: 1926879 HomoloGene: 11094 GeneCards: TAF8

Transcription initiation factor TFIID subunit 8 is a protein that in humans is encoded by the TAF8 gene.

This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.


TAF8 Wikipedia