Synge is an Irish and British surname. Notable people with the name include:
Cathleen Synge (born 1923), Canadian mathematician a.k.a. Cathleen Synge Morawetz
Edward Synge (archbishop of Tuam) (1659–1741), Anglican clergyman who served in the Church of Ireland
Edward Synge (bishop of Elphin) (1691–1762), Anglican bishop in the Church of Ireland
Edward Hutchinson Synge (1890-1957), inventor of the near-field optical microscope
John Lighton Synge (1897-1995), Irish mathematician and physicist
John Millington Synge (1871-1909), Irish playwright, poet, and prose writer
Nicholas Synge (died 1771), 18th-century Irish Anglican priest
Patrick Synge (1910-1982), British botanist, writer and plant hunter
Richard Laurence Millington Synge (1914-1994), British biochemist
Violet Synge