Sulfopropanediol 3 dehydrogenase

Sulfopropanediol 3-dehydrogenase (EC 1.1.1.308, DHPS 3-dehydrogenase (sulfolactate forming), 2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming), dihydroxypropanesulfonate 3-dehydrogenase, hpsN (gene)) is an enzyme with systematic name (R)-2,3-dihydroxypropane-1-sulfonate:NAD⁺ 3-oxidoreductase. This enzyme catalyses the following chemical reaction

(R)-2,3-dihydroxypropane-1-sulfonate + 2 NAD⁺ + H₂O ⇌ (R)-3-sulfolactate + 2 NADH + 2 H⁺

The enzyme is involved in degradation of (R)-2,3-dihydroxypropanesulfonate.