ATCvet code QJ01EQ13 (WHO) PubChem CID 17134 ChemSpider 16218 | CAS Number 2447-57-6 DrugBank DB01299 Molar mass 310.33 g/mol | |
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AHFS/Drugs.com International Drug Names | ||
Sulfadoxine (also spelled sulphadoxine) is an ultra-long-lasting sulfonamide used in combination with pyrimethamine to treat malaria.
It was previously used to prevent malaria but due to high levels of resistance, this use is no longer recommended routinely.
It is also used, usually in combination with other drugs, to treat or prevent various infections in livestock.
Mechanism of action
Sulfadoxine competitively inhibits dihydropteroate synthase, interfering with folate synthesis.
References
Sulfadoxine Wikipedia(Text) CC BY-SA