Succinate semialdehyde dehydrogenase (acylating)

Updated on Dec 30, 2024

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EC number 1.2.1.76 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Succinate-semialdehyde dehydrogenase (acylating) (EC 1.2.1.76, succinyl-coA reductase, coenzyme-A-dependent succinate-semialdehyde dehydrogenase) is an enzyme with systematic name succinate semialdehyde:NADP⁺ oxidoreductase (CoA-acylating). This enzyme catalyses the following chemical reaction

succinate semialdehyde + CoA + NADP⁺ ⇌ succinyl-CoA + NADPH + H⁺

Catalyses the NADPH-dependent reduction of succinyl-CoA to succinate semialdehyde.

References

Succinate-semialdehyde dehydrogenase (acylating) Wikipedia

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