Sticky mouse

Sticky mouse is a murine mutant possessing a defective alanyl-tRNA synthetase (AARS) and therefore used in investigational studies into mechanisms of neuronal degeneration. Its most immediately obvious symptom is a sticky secretion on the mouse's fur (thus the name); however, it is accompanied by lack of muscle control, ataxia, alopecia, loss of Purkinje cells in the cerebellum, and eventually, death.

Sticky mouse is one of several animal mutants that are known to have problems in mRNA translation and are used in studies.