Rahul Sharma (Editor)

Steroid 15beta monooxygenase

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EC number
  
1.14.15.8

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

Steroid 15beta-monooxygenase (EC 1.14.15.8, cytochrome P-450meg, cytochrome P450meg, steroid 15beta-hydroxylase, CYP106A2, BmCYP106A2) is an enzyme with systematic name progesterone,reduced-ferredoxin:oxygen oxidoreductase (15beta-hydroxylating) . This enzyme catalyses the following chemical reaction

progesterone + reduced ferredoxin + O2 ⇌ 15beta-hydroxyprogesterone + oxidized ferredoxin + H2O

The enzyme from Bacillus megaterium hydroxylates a variety of 3-oxo-Delta4-steroids in position 15beta.

References

Steroid 15beta-monooxygenase Wikipedia
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