EC number 4.1.99.14 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 37290-70-3 BRENDA BRENDA entry KEGG KEGG entry | |
Spore photoproduct lyase (EC 4.1.99.14, SAM, SP lyase, SPL, SplB, SplG) is a radical SAM enzyme that repairs a particular kind of lesion that arises upon UV-radiation of bacterial DNA. This repair mechanism is one of the reasons for the resilience of certain bacterial spores. Through a series of radical reactions the photodimer, 3 5-thyminyl-5,6-dihydrothymine, is disconnected to give back two functional thymine rings.
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Spore photoproduct lyase Wikipedia(Text) CC BY-SA