EC number 4.1.99.14 ExPASy NiceZyme view | CAS number 37290-70-3 | |
Spore photoproduct lyase (EC 4.1.99.14, SAM, SP lyase, SPL, SplB, SplG) is a radical SAM enzyme that repairs a particular kind of lesion that arises upon UV-radiation of bacterial DNA. This repair mechanism is one of the reasons for the resilience of certain bacterial spores. Through a series of radical reactions the photodimer, 3 5-thyminyl-5,6-dihydrothymine, is disconnected to give back two functional thymine rings.
References
Spore photoproduct lyase Wikipedia(Text) CC BY-SA