Spiteri is a common Maltese surname deriving from the Italian word Ospitalieri, meaning Hospitallers. It was sometimes given to illegitimate children left at the ruota during the rule of the Order of St. John. Notable people with the surname include:
Donat Spiteri, Maltese religious leader and author
Glenn Spiteri, A.R.P.S. Photographer (New York & Scotland)
Mary Spiteri, Maltese cabaret artiste
Matthew Spiteri, Maltese Water Skier
Oliver Spiteri, Maltese soccer manager and former player
Renzo Spiteri, Maltese musician
Salvino Spiteri, founder of Malta Workers' Union (UĦM)
Sharleen Spiteri, singer-songwriter; guitarist; lead vocalist of the Scottish pop-rock band Texas
Stephen C. Spiteri, Maltese military historian
