Trade names Renormax Routes ofadministration Oral Molar mass 466.616 g/mol Bioavailability 50% | Pregnancycategory D ATC code C09AA11 (WHO) CAS ID 83647-97-6 | |
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AHFS/Drugs.com International Drug Names Legal status In general: ℞ (Prescription only) | ||
Spirapril hydrochloride (Renormax) is an ACE inhibitor antihypertensive drug used to treat hypertension. It belongs to dicarboxy group of ACE inhibitors.
Like many ACE inhibitors, this prodrug is converted to the active metabolite spiraprilat following oral administration. Unlike other members of the group, it is eliminated both by renal and hepatic routes, which may allow for greater use in patients with renal impairment. However, data on its effect upon the renal function are conflicting.
References
Spirapril Wikipedia(Text) CC BY-SA