Sphinganine C4 monooxygenase

Updated on Dec 29, 2024

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EC number 1.14.13.169 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Sphinganine C4-monooxygenase (EC 1.14.13.169, sphingolipid C4-hydroxylase, SUR2 (gene), SBH1 (gene), SBH2 (gene)) is an enzyme with systematic name sphinganine,NADPH:oxygen oxidoreductase (C4-hydroxylating). This enzyme catalyses the following chemical reaction

sphinganine + NADPH + H⁺ + O₂ ⇌ phytosphingosine + NADP⁺ + H₂O

Sphinganine C4-monooxygenase is involved in the biosynthesis of sphingolipids in yeast and plants.

References

Sphinganine C4-monooxygenase Wikipedia

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