Spangler is a surname. Notable people with the surname include:
Al Spangler, American baseball playerBud Spangler (1938–2014), American musicianDavid Spangler (congressman), deceased United States Congressman from OhioDavid Spangler, American spiritualistDonald H. Spangler, United States Naval officerEdmund Spangler, alleged conspirator of the Abraham Lincoln assassinationFrank Spangler, LAPD official involved with the O.J. Simpson investigationHarrison E. Spangler, chairman of the Republican National Committee 1940-44Jacob Spangler, deceased United States Congressman from PennsylvaniaJames Murray Spangler, invented an electric vacuum cleanerJean Spangler, Hollywood dancer and model who disappeared in 1949Lester Spangler, deceased Indy 500 race car driverPaul Spangler Naval surgeon, Senior long distance runnerSpanky Spangler, daredevil performer and youngest Green BeretSteve Spangler, Emmy Award winning author and professional speakerFictional characters:
Edwin Spangler, see Characters of Malcolm in the Middle