Entrez 221833 | Ensembl ENSG00000164651 | |
External IDs MGI: 2443471 HomoloGene: 18548 GeneCards: SP8 | ||
Transcription factor Sp8 also known as specificity protein 8 (SP-8) or Btd transcription factor (buttonhead) is a protein that in humans is encoded by the SP8 gene. Sp8 is a transcription factor in the Sp/KLF family.
Function
Sp8 mediates limb outgrowth during early development. Sp8 deletion in mice resulted in severe exencephaly.
References
Sp8 transcription factor Wikipedia(Text) CC BY-SA