Sosa is a Spanish surname. Notable people with that name include:
Alex Sosa, fictional drug lord from the 1983 film ScarfaceAntonieta Sosa, Venezuelan performance artistArlenis Sosa, Dominican modelArturo Sosa (born 1948), Superior General of the Jesuit orderDavid Sosa, American philosopher, son of Ernest SosaElías Sosa (born 1950), Dominican Republic baseball playerErnest Sosa, American philosopher, father of David SosaFrancisco Sosa, Paraguayan football forwardGilberto Sosa, Mexican boxerJerónimo de Sosa, 17th-century Spanish Franciscan friar and genealogistJorge Sosa, Dominican baseball pitcherJosé Ernesto Sosa, Argentine footballerJosé José (born José Rómulo Sosa Ortiz), Mexican singerJulio Sosa (guitarist), Argentine guitaristJulio Sosa, Uruguayan tango singerMercedes Sosa, Argentine singerPatricia Sosa (singer) (born 1956), Argentine singerPorfirio Lobo Sosa, Honduran politicianRoberto Sosa, Argentine footballerSammy Sosa (born 1968), Dominican baseball playerTomás Méndez Sosa, Mexican singer and composerÉdgar Sosa (basketball) (born 1988), American–Dominican basketball playerÉdgar Sosa (boxer) (born 1979), Mexican boxerChief Keef, American rapper with the nickname Sosa