Sosa is a Spanish surname. Notable people with that name include:
Alex Sosa, fictional drug lord from the 1983 film Scarface
Antonieta Sosa, Venezuelan performance artist
Arlenis Sosa, Dominican model
Arturo Sosa (born 1948), Superior General of the Jesuit order
David Sosa, American philosopher, son of Ernest Sosa
Elías Sosa (born 1950), Dominican Republic baseball player
Ernest Sosa, American philosopher, father of David Sosa
Francisco Sosa, Paraguayan football forward
Gilberto Sosa, Mexican boxer
Jerónimo de Sosa, 17th-century Spanish Franciscan friar and genealogist
Jorge Sosa, Dominican baseball pitcher
José Ernesto Sosa, Argentine footballer
José José (born José Rómulo Sosa Ortiz), Mexican singer
Julio Sosa (guitarist), Argentine guitarist
Julio Sosa, Uruguayan tango singer
Mercedes Sosa, Argentine singer
Patricia Sosa (singer) (born 1956), Argentine singer
Porfirio Lobo Sosa, Honduran politician
Roberto Sosa, Argentine footballer
Sammy Sosa (born 1968), Dominican baseball player
Tomás Méndez Sosa, Mexican singer and composer
Édgar Sosa (basketball) (born 1988), American–Dominican basketball player
Édgar Sosa (boxer) (born 1979), Mexican boxer
Chief Keef, American rapper with the nickname Sosa
