Sokoloff, a surname, may refer to:
Alexandra Sokoloff, American novelist and screenwriter
Eleanor Sokoloff (born 1914), American pianist
Kenneth Sokoloff (1952-2007), American economic historian
Marla Sokoloff (born 1980), American actress
Melvin Sokoloff (1929-1990), stage name Mel Lewis, American jazz musician/drummer
Nahum Sokolow or Sokoloff (1859-1936), Zionist leader and journalist
Nikolai Sokoloff (1886-1965), Russian American conductor and violinist
Vladimir Sokoloff (1889-1962), Hollywood character actor born in Russia