Soffer is a surname. Notable people with the name include:
Adi Soffer, Israeli footballer
Arnon Soffer (born 1935), Israeli geographer and a professor
Avi Soffer, Israeli soccer player
Bernard H Soffer co-inventor of Solid-state dye lasers
Donald Soffer (born 1933), American real estate developer
Jesse Lee Soffer (born 1985), American actor
Ram Soffer (born 1965), Israeli chess grandmaster
Sasson Soffer (1925–2009), American abstract painter and sculptor