Smither is a surname. People so named include:
Beri Smither (born 1971), American model
Bob Smither (born 1944), Libertarian Party Texas congressional candidate
Chris Smither (born 1944), American folk-blues singer, guitarist, and songwriter
Elizabeth Smither (born 1941), New Zealand poet and writer
Henry Smither (1873–?), US Army officer and football coach
Denise Orme, stage name of Jessie Smither (1885–1960), English music hall singer, actress and musician
Michael Smither (born 1939), New Zealand painter and composer, husband of Elizabeth Smither
Sheryl Smither (born 1960), maiden name of USAF veteran, wife, and mother.