Smalls is a surname. Notable people with the surname include:
Bertie Smalls (1935–2008), noted British supergrass
Biggie Smalls, former name of The Notorious B.I.G.
Charlie Smalls (1943–87), composer and songwriter
Cliff Smalls (1918-2008), American jazz trombonist, pianist, conductor and arranger
Fred Smalls (born 1963), American football linebacker
Joan Smalls, Puerto Rican fashion model
Robert Smalls (1839–1915), slave who, during and after the American Civil War, became a ship's pilot, sea captain and politician
Tiger Smalls, American boxing trainer
Tionna T. Smalls, American author and media personality
Tommy Smalls (1926/7-72), New York radio disc jockey known as "Dr. Jive"
Fictional characters:
Derek Smalls, bassist in the parody heavy metal band Spinal Tap (band)
