Puneet Varma (Editor)

Small nucleolar RNA snR66

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Symbol
  
snosnR66

GO
  
0006396 0005730

Domain
  
Eukaryote

Rfam
  
RF00477

SO
  
0000593

Small nucleolar RNA snR66

RNA type
  
Gene; snRNA; snoRNA; CD-box

snoRNA snR66 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. snoRNA snR66 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR66 was initially discovered using a computational screen of the Saccharomyces cerevisiae genome.

References

Small nucleolar RNA snR66 Wikipedia