Harman Patil (Editor)

Small nucleolar RNA SNORA75

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Symbol
  
SNORA75

Rfam
  
RF00072

SO
  
0000594

Alt. Symbols
  
U23

GO
  
0006396 0005730

Domain
  
Eukaryote

Small nucleolar RNA SNORA75 httpsuploadwikimediaorgwikipediacommonsthu

RNA type
  
Gene; snRNA; snoRNA; H/ACA-box

U23 belongs to the H/ACA class of snoRNAs. snoRNAs bind a number of proteins (including dyskerin, Gar1p and Nop10p in the case of the H/ACA class) to form snoRNP complexes. This class are thought to guide the sites of modification of uridines to pseudouridines by forming direct base pairing interactions with substrate RNAs. Targets include ribosomal and spliceosomal RNAs as well as the Trypanosoma spliced leader RNA (SL RNA) as possibly other, still unknown cellular RNAs. U23 can direct the pseudouridylation of U97 in human 18S rRNA. U23 is encoded within intron 12 of the nucleolin gene in human, mouse, rat chicken, and Xenopus laevis.

References

Small nucleolar RNA SNORA75 Wikipedia