Supriya Ghosh (Editor)

Small nucleolar RNA R24

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Symbol
  
snoR24

GO
  
0006396 0005730

Domain
  
Eukaryote

Rfam
  
RF00132

SO
  
0000593

Small nucleolar RNA R24

RNA type
  
Gene; snRNA; snoRNA; CD-box

Small nucleolar RNA R24 (also known as snoRNA R24) is a non-coding RNA (ncRNA) molecule identified in plants which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.

R24 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.

snoR24 was originally identified in Arabidopsis thaliana and is proposed to acts as a methylation guide for 18S ribosomal RNA (rRNA) in plants.

References

Small nucleolar RNA R24 Wikipedia