Supriya Ghosh (Editor)

Sivelestat

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Routes of administration
  
IV

CAS Number
  
127373-66-4

Molar mass
  
434.46 g/mol

ATC code
  
None

PubChem CID
  
107706

Sivelestat httpsuploadwikimediaorgwikipediacommons55

AHFS/Drugs.com
  
International Drug Names

Legal status
  
US: Not FDA approved In general: ℞ (Prescription only)

Sivelestat (INN, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase.

It is used in the treatment of acute respiratory failure and preliminary studies show it may also improve neuropathic pain.

Synthesis

Sivelestat is synthesised as follows:

References

Sivelestat Wikipedia