Type Whole antibody CAS Number 1318075-13-6 | Source Humanized ATC code none IUPHAR/BPS 8412 | |
Simtuzumab (INN; formerly GS 6624) is a humanized monoclonal antibody designed for the treatment of fibrosis. It binds to LOXL2 and acts as an immunomodulator. In January 2016, Gilead Sciences terminated its Phase 2 clinical study in patients with idiopathic pulmonary fibrosis (IPF) due to lack of efficacy.
References
Simtuzumab Wikipedia(Text) CC BY-SA