Silliman is a surname. Notable people with the surname include:
Aldine Silliman Kieffer (1840–1904), American musician
Benjamin Silliman (1779–1864), American chemist
Benjamin Silliman Jr. (1816–1885), American chemist
Gold Selleck Silliman (1732–1790), American attorney and Revolutionary War figure
Horace Brinsmade Silliman (1825-1910), founder of Silliman University
Randolph Silliman Bourne (1886–1918), American writer
Robert Hillyer a.k.a. Robert Silliman Hillyer (1895–1961), American poet
Ron Silliman (1946– ), American poet