Shuttleworth is the surname of a family that appears to have originated in either Lancashire or Yorkshire no later than the 14th century. It may refer to:
A. R. B. Shuttleworth, British politician
Anna Shuttleworth, British cellist
Archie Shuttleworth, character from Coronation Street played by Roy Hudd
Bobby Shuttleworth, American goalkeeper
Charles Shuttleworth, Canadian politician
Sir James Kay-Shuttleworth, 1st Baronet, English politician
Jane and John Shuttleworth, co-founders of Mother Earth News magazine
John Shuttleworth (industrialist), English industrialist
John Shuttleworth (character), created by English comic actor Graham Fellows
Ken Shuttleworth (architect), English architect
Ken Shuttleworth (cricketer), English cricketer
Mark Shuttleworth, South African entrepreneur
Obadiah Shuttleworth, English composer
Ughtred Kay-Shuttleworth, 1st Baron Shuttleworth, British politician
Richard Shuttleworth, see disambiguation
Robert James Shuttleworth, (1810–1874) Swiss-British malacologist
Timothy Shuttleworth (born 1997), British swimmer