Shapira is a surname, and may refer to:
Anita Shapira
Avraham Shapira, rabbi
Benjamin Shapira, Israeli biochemist.
Berechiah Berak ben Isaac Eisik Shapira, 17th-century rabbi
David Shapira
Haim-Moshe Shapira, Israeli politician
Moshe Shmuel Shapira, rabbi
Moses Shapira
Moses Wilhelm Shapira
Nimrod Shapira Bar-Or (born 1989), Israeli swimmer
Yitzhak Shapira, author of The King's Torah
Yosef Shapira, Israeli judge and State Comptroller of Israel
Shapira (Tel Aviv neighborhood)
