Shake It Up may refer to:
Shake It Up (Boney James & Rick Braun album), 2000
Shake It Up (The Cars album), 1981
"Shake It Up" (The Cars song), the title song
"Shake It Up" (Divine song), 1983
"Shake It Up" (Kumi Koda song), 2005
"Shake It Up" (Selena Gomez song), 2011
"Shake It Up", a song by Elizabeth Daily from the 1983 film Scarface, included in its soundtrack
"Shake It Up, song by The Parlotones, 2012
Shake It Up (U.S. TV series), a U.S. Disney Channel original series that aired from 2010–2013
Shake It Up: I Love Dance soundtrack, 2013
Shake It Up (Indian TV series), a 2013 Indian adaptation of the American series