Seybold is a surname. Notable people with the surname include:
John Seybold (criminal) (1923–2005), American jewel thief who authored The Home Invaders: Confessions of a Cat Burglar under the pen name Frank Hohimer
John States Seybold (1897–1984), Governor of the Panama Canal Zone from 1952 to 1956
John W. Seybold (1916–2004), the father of computer typesetting
Natalie Seybold (born 1965), American former pair skater
Patricia Seybold, CEO of Patricia Seybold Group
Socks Seybold (1870–1921), outfielder in Major League Baseball
Wayne Seybold (born 1963), the mayor of Marion, Indiana, former pair skater representing the United States