Serine 3 dehydrogenase

In enzymology, a serine 3-dehydrogenase (EC 1.1.1.276) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are L-serine and NADP⁺, whereas its 3 products are 2-ammoniomalonate semialdehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is L-serine:NADP⁺ 3-oxidoreductase.