Sequoyitol dehydrogenase

In enzymology, a sequoyitol dehydrogenase (EC 1.1.1.143) is an enzyme that catalyzes the chemical reaction

5-O-methyl-myo-inositol + NAD⁺ ⇌ 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H⁺

Thus, the two substrates of this enzyme are 5-O-methyl-myo-inositol and NAD⁺, whereas its 3 products are 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is 5-O-methyl-myo-inositol:NAD⁺ oxidoreductase. This enzyme is also called D-pinitol dehydrogenase.