Kalpana Kalpana (Editor)

Sentinel cell

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Sentinel cells refer to cells in the body's first line of defense, which embed themselves in tissues such as skin Sentinel cells can refer to specific antigen-presenting cells, such as:

  • Macrophages
  • Kupffer cells - in the liver
  • Langerhans cells - in the skin and mucosa
  • Alveolar macrophages - in the lungs
  • Microglia - in the brain
  • Dendritic cells
  • Sentinel cells can also refer to cells that are normally not specialized antigen-presenting cells such as:

  • Mast cells
  • Specialized T cells
  • Sometimes tissue cells not part of the immune system such as are also referred to as Sentinel cells:

  • Fibroblasts
  • Epithelial cells
  • References

    Sentinel cell Wikipedia


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