EC number 4.4.1.16 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 82047-76-5 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a selenocysteine lyase (EC 4.4.1.16) is an enzyme that catalyzes the chemical reaction
L-selenocysteine + reduced acceptorThus, the two substrates of this enzyme are L-selenocysteine and reduced acceptor, whereas its 3 products are selenide, L-alanine, and acceptor.
This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-selenocysteine selenide-lyase (L-alanine-forming). Other names in common use include selenocysteine reductase, and selenocysteine beta-lyase. This enzyme participates in selenoamino acid metabolism. It employs one cofactor, pyridoxal phosphate.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1I29, 1JF9, 1KMJ, and 1KMK.