The surname Seguí is a surname. Notable people with the surname include:
Antonio Seguí (born 1934), Argentine painter and printmakerDiego Seguí (born 1937), Cuban former Major League Baseball pitcherEnrique Eguía Seguí (born 1962), prelate of the Roman Catholic ChurchJuan Seguí (born 1947), Spanish former sport shooter who competed in the 1976 Summer OlympicsLuis Miguel Seguí (born 1972), Spanish actor and producerSalvador Seguí (1886–1923), Catalan anarcho-syndicalist