Secco is a surname of Italian origin, which means dry. It may refer to:André Secco (b. 1991), Brazilian Software Engineer and .NET Specialist
Alessio Secco (b. 1970), Italian professional football manager
Deborah Secco (b. 1979), Brazilian actress
Louis Secco (b. 1927), Canadian Olympic ice hockey player
Andres Secco (b.1959), A reputed Chemical Engineer in Chile, South American Judo Contestant
Secco is a musical term meaning "dry", "without resonance" or "quick".
Secco or Fresco-secco is a type of mural painting where paint is applied to dry plaster on a wall.