Searle is a surname. Notable people with the surname include:
Berni Searle (born 1964), South African photographer and installation artist
Charles Edward Searle, British academic, Vice-Chancellor of Cambridge University 1888–89
Damon Searle (born 1971), Welsh footballer
Frank Searle (1921–2005), British photographer of the Loch Ness Monster
Frank Searle (1874-1948), Chief Engineer of the London General Omnibus Company
George Frederick Charles Searle (1864–1954), British physicist
George Mary Searle (1839–1918), American astronomer
Greg Searle (born 1972), British Olympic rower, brother of Jonny Searle
Helen Searle (1834–1884), American painter
Henry Ernest Searle (1866–1899), Australian professional sculler
Humphrey Searle (1915–1982), British composer
James Searle (c. 1730–1797), American merchant
John Searle (born 1932), American philosopher, famous for work on consciousness and for his speech act theory
Jonny Searle (born 1969), British Olympic rower, brother of Greg Searle
Ken Searle (born 1951), Australian artist
Michael Searle, Australian rugby league football personality
Robert Searle, English pirate of the mid-17th century
Rod Searle (1920–2014), American politician
Ron Searle, Canadian mayor from 1976 to 1978
Ronald Searle (1920–2011), British artist and cartoonist
Ryan Searle (born 1989), Australian baseball player
Shayle R. Searle, American statistician