Rahul Sharma (Editor)

Scytalone dehydratase

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EC number
  
4.2.1.94

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

In enzymology, a scytalone dehydratase (EC 4.2.1.94) is an enzyme that catalyzes the chemical reaction

scytalone 1,3,8-trihydroxynaphthalene + H2O

Hence, this enzyme has one substrate, scytalone, and two products, 1,3,8-trihydroxynaphthalene and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming). This enzyme is also called scytalone 7,8-hydro-lyase.

Structural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1IDP, 1STD, 2STD, 3STD, 4STD, 5STD, 6STD, and 7STD.

References

Scytalone dehydratase Wikipedia