Scot is a surname. Notable people with the surname include:
Daniel Scot (21st century), co-director of Ibrahim Ministries InternationalLewis Scot (17th century), English pirateMichael Scot (c. 1175 – 1232), Scottish astrologerReginald Scot (c. 1538 – 1599), English authorRobert Scot (1744–1823), American artistThomas Scot (died 1660), English Member of ParliamentWilliam Scot (13th century), Roman Catholic priest