Type Private Area served Worldwide | Headquarters New York, NY Founded 1990 | |
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Industry Life Sciences
Materials Science
Software
Computational Chemistry
Cheminformatics Key people Ramy Farid (President & CEO), Charles Ardai (Chairman of the Board) Products Small-Molecule Drug Discovery Suite
Biologics Suite
Materials Science Suite
Discovery Informatics Suite
PyMOL Founders William A. Goddard III, Richard A. Friesner, William Andrew Goddard III Profiles | ||
Schrödinger, LLC is an American software company that develops chemical simulation software for use in pharmaceutical, biotechnology, and materials science research. The company provides products ranging from general molecular modeling programs to a full suite of chemical simulation and drug design software, including ligand- and structure-based methods. It also provides products in various research areas, including small molecule modeling and simulations, macromolecular modeling and simulations, lead discovery, lead optimization, and visualization and automation. The company’s software helps scientists to accelerate their research and development activities, as well as to make novel discoveries. Founded in 1990, Schrödinger is headquartered in New York City, with operations in Oregon, California, Massachusetts, Germany, France, India, the United Kingdom, and Japan.
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Company
Schrödinger major offices are located New York and Portland. Bill Gates invested $10 million in 2010 through his investment company Cascade under conditions that it is to be spent only for research and development. Gates invested another $20 million in Schrödinger in December 2012. In September 2013, Nimbus Discovery, a strategic partner of Schrödinger, was named one of FierceBiotech's "2013 Fierce 15" in recognition of the company's novel business strategies and technology. In November 2013, Schrödinger, in collaboration with Cycle Computing and the University of Southern California set a record for the world's largest and fastest cloud computing run by using 156,000 cores on Amazon Web Services to screen over 205,000 molecules for materials science research. This work was a follow up to a collaboration in 2012 in which Cycle Computing created a 50,000 core virtual supercomputer using Amazon infrastructure and Schrödinger's Glide program was used to analyze 2.1 million compounds in only 3 hours.
Products
Schrödinger's full product offerings range from general molecular modeling programs to a comprehensive suite of drug design software, as well as a suite for materials research. Python APIs exist for most of the software tools developed by Schrödinger, making it possible to build custom workflows. Some of its software are: Canvas, Glide, Induced Fit, Phase, SiteMap, WaterMap, PyMOL, and FEP+.
Services
In addition to its software platforms Schrödinger provides professional services including custom software development and training, computer-cluster design and implementation, and research-based drug discovery projects. These professional services are provided to commercial, academic, and government organizations to assist with small-molecule design, biologics design, materials science applications, and implementation of enterprise-level informatics.
Partners
Schrödinger is a partner with Nimbus Discovery, which uses Schrödinger’s drug screening and design platform in combination with a virtual, globally distributed model for drug discovery. In April 2016, Nimbus announced that Gilead will acquire Nimbus Apollo, Inc., a wholly owned subsidiary of Nimbus Therapeutics, and its Acetyl-CoA Carboxylase (ACC) inhibitor program. Nimbus Therapeutics will receive an upfront payment of $400 million, with the potential to receive an additional $800 million in development-related milestones over time. In April 2015, Sanofi signed a $120M drug discovery deal with Schrödinger. In January 2016, Schrödinger announced a research collaboration with Pfizer to develop a computational model for predicting key biotherapeutic properties.
Awards and Recognition
In recognition of his contributions to original research in the field of computational chemistry, Schrödinger founder Prof. Richard A. Friesner was elected to the National Academy of Sciences in 2016, and to the American Academy of Arts and Sciences in 2008. In 2014, Schrödinger was awarded the BioIT World Best Practices Award in the category of IT Infrastructure.