Sandhu is a Jat clan in the Punjab Region of India and Pakistan.
Notable people with the surname, who may or may not be affiliated to the clan, include:
Gurinder Sandhu (born 1993), Australian professional cricketer
Gurjit Sandhu (born 1992), English cricketer
Harinder Pal Sandhu, (born 1989), Indian squash player
Harpreet Sandhu (actor) (born 1979), Indian actor, director, writer, music director, editor, cinematographer and poet
Jasbir Sandhu (born 1966), Canadian politician and Member of Parliament
Kamaljeet Sandhu, Indian athlete
Nandish Sandhu, Indian model and television actor
Manavjit Singh Sandhu (born 1976), Indian sport shooter and three-time Olympian
Nick Sandhu (born 1962), Indian field hockey player
Peter Sandhu, Canadian politician and Member of the Legislative Assembly of Alberta
Sahil Sandhu (born 1991), Canadian football (soccer) player
Surinder Sandhu, Indian sarangi player and composer
Tommy Sandhu (born 1976), British DJ, remixer, producer and television presenter
Vattan Sandhu, Indian Punjabi singer and actor