Samuels is a surname. Notable people with the surname include:
Andrew Samuels, Jungian psychologist
Arthur Warren Samuels, Irish politician
Chris Samuels, American football player
Dale Samuels, American football player
Dave Samuels, American musician
David Samuels (political scientist), political science professor
David Samuels (EastEnders), fictional character in BBC TV soap opera EastEnders
David Samuels (writer) (born 1967), American author
Dover Samuels, New Zealand politician
Ernest Samuels, American biographer
Giovonnie Samuels, American actress
Gordon Samuels, Australian politician
Howard J. Samuels, American politician
Jamar Samuels (born 1989), American basketball player for Bnei Herzliya of the Israeli Basketball Premier League
Joel Samuels, fictional character
John Samuels, American actor
Lawrence Samuels, arena football player
Lesser Samuels, screenwriter
Lynn Samuels, radio host
Marlon Samuels, cricketer
Maxwell Samuels, Belizean politician
Moss Turner-Samuels, UK politician
Robert Samuels, cricketer
Ron Samuels, film producer
Samardo Samuels (born 1989), Jamaican basketball player
Theo Samuels, South African rugby union player
Tony Samuels, American football player
Warren Samuels, economist and historian of economic thought