Sam is a surname. Notable people with the name include:
Chief Alfred Sam (c.1880–1930s), Gold Coast trader and Back-to-Africa pioneerEliza Sam or Cen Lixiang (born 1984), Chinese-Canadian actressLeman Sam (born 1951), Turkish singer and songwriterMichael Sam (born 1990), American gridiron football playerP. K. Sam (born 1983), American gridiron football playerŞevval Sam (born 1973), Turkish singer and actressTirésias Simon Sam (1835–1916), Haitian politician, President of Haiti 1896–1902Vilbrun Guillaume Sam (1859–1915), Haitian politician, President of Haiti 1915