Sam is a surname. Notable people with the name include:
Chief Alfred Sam (c.1880–1930s), Gold Coast trader and Back-to-Africa pioneer
Eliza Sam or Cen Lixiang (born 1984), Chinese-Canadian actress
Leman Sam (born 1951), Turkish singer and songwriter
Michael Sam (born 1990), American gridiron football player
P. K. Sam (born 1983), American gridiron football player
Şevval Sam (born 1973), Turkish singer and actress
Tirésias Simon Sam (1835–1916), Haitian politician, President of Haiti 1896–1902
Vilbrun Guillaume Sam (1859–1915), Haitian politician, President of Haiti 1915