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In pathology, salt-and-pepper chromatin, also salt-and-pepper nuclei and stippled chromatin, refers to cell nuclei that demonstrate granular chromatin (on light microscopy).
Salt-and-pepper chromatin is typically seen in endocrine tumours such as medullary thyroid carcinoma, neuroendocrine tumours and pheochromocytoma.
References
Salt-and-pepper chromatin Wikipedia(Text) CC BY-SA