Salerno is a surname. Notable people with the surname include:
Anthony Salerno (1911–1992), Italian-American mobster
Charles Salerno, American businessperson
Enrico Maria Salerno (1926–1994), Italian actor
Frederic Salerno (21st century), corporate director of the Viacom Corporation
Francesco Carmelo Salerno (1925–1998), Member of the Italian parliament and Football Club Manager
Joseph Salerno (21st century), Austrian School economist
Nicola Salerno (1910–1969), Italian lyricist
Randy Salerno (1963–2008), American news anchor
Robert Salerno (21st century), American film producer
Sabrina Salerno (born 1968), Italian singer, showgirl, model, actress and record producer
Shane Salerno (born 1972), American screenwriter and producer
Tony Salerno (born 1969), American voice actor
