Saint-Pierre or St Pierre or St. Pierre is the surname of:
Charles-Irénée Castel de Saint-Pierre (1658–1743), proposed the creation of a European league of 18 sovereign states
Guy Saint-Pierre (born 1934), Canadian politician and businessman
Jacques-Henri Bernardin de Saint-Pierre (1737–1814), French writer and botanist
Liliane Saint-Pierre (born 1948), Belgian singer
Marie-Josée Saint-Pierre (born 1978), Canadian filmmaker
Paul Matthew St. Pierre (active from 1992), Canadian academic and writer
Richard Saint-Pierre, one of the first translators of, and possibly discoverer of, the Gospel of Thomas
