Saint is a surname shared by several notable people, including:
Crosbie E. Saint (born 1936), American generalEva Marie Saint (born 1924), American actressJohnny Saint (born 1941), English professional wrestlerLawrence Saint (1885–1961), American stained glass artistNate Saint (1923–1956), American evangelical missionary pilot killed in Ecuador (brother of Rachel)Percy Saint (1870-1958), American politicianRachel Saint (1914–1994), American evangelical Christian missionary who worked in Ecuador (sister of Nate)Saint Saffold (born 1944), American football playerSilvia Saint (born 1976), Czech porn actressSteve Saint (born 1951), Ecuadorian/American business entrepreneur, pilot and author (son of Nate)