Sackville is a surname. Notable people with the surname include:
Sir Richard Sackville (ca. 1507 – 21 April 1566)
Baron Sackville
Lionel Edward Sackville-West, 3rd Baron Sackville
Victoria Sackville-West, Baroness Sackville
Edward Sackville-West, 5th Baron Sackville (1901–1965), writer and musicologist
Viscount Sackville
George Germain, 1st Viscount Sackville (1716–1785)
Charles Sackville-Germain, 2nd Viscount Sackville, 5th Duke of Dorset (1767–1843)
Reginald Windsor Sackville, 7th Earl De La Warr
Lady Margaret Sackville
Vita Sackville-West
Charles Sackville, 6th Earl of Dorset
Lionel Sackville, 1st Duke of Dorset
Thomas Sackville, 1st Earl of Dorset
Herbrand Sackville, 9th Earl De La Warr
