Sabine is a surname. Notable people with the surname include:
Charles Sabine (born 1960), English TV journalist and advocate for patients with degenerative brain disease
David Sabine (born 1966), English cricketer
Sir Edward Sabine (1788–1883), Irish astronomer, scientist, ornithologist and explorer
Elizabeth Sabine (born 1923), Australian voice coach
George Holland Sabine (1880–1961), American professor and author of philosophy
Joseph Sabine (1770–1837), English lawyer and naturalist
Joseph Sabine (British Army officer) (c. 1661–1739), British general and Member of Parliament
Lorenzo Sabine (1803–1877), U.S. Representative from Massachusetts
Roy Sabine, English rugby union and rugby league footballer of the 1950s and '60s, and rugby league coach of the 1970s
Thierry Sabine, (1949–1986), French motorcycle racer and organiser of the Paris-Dakar rally raid
Wallace Clement Sabine (1868–1919), physicist, who defined the Sabin unit of sound energy absorption (so named in his honor)
William Sabine (1491–1543), English politician