Species Human Entrez 8871 | Human Mouse Ensembl ENSG00000078269 | |
Aliases SYNJ2, INPP5H, synaptojanin 2 External IDs MGI: 1201671 HomoloGene: 117703 GeneCards: SYNJ2 | ||
Synaptojanin 2 is a protein that in humans is encoded by the SYNJ2 gene.
Function
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
References
SYNJ2 Wikipedia(Text) CC BY-SA